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Antigenic Specificity | GPM6A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GPM6A (NP 005268.1). |
Other Names | [M6A; GPM6] |
Gene, Accession # | [GPM6A], NCBI: AAH37853.1, UniProt: P51674 |
Catalog # | MBS8547572 |
Price | $280 |
Order / More Info | GPM6A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |