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Antigenic Specificity | Integrin beta4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Integrin beta4 Polyclonal Antibody detects endogenous levels of Integrin beta4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. ITGB4 encodes Integrin beta-4, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atres |
Immunogen | Immunogen: Synthesized peptide derived from human Integrin beta4 around the non-phosphorylation site of Y1510 |
Other Names | [Rabbit Integrin beta4; Integrin beta-4; GP150; CD antigen CD104] |
Gene, Accession # | [ITGB4], Gene ID: 3691, NCBI: NP_000204.3, UniProt: P16144 |
Catalog # | MBS9702331 |
Price | $130, $220, $325 |
Order / More Info | Integrin beta4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |