Edit |   |
Antigenic Specificity | PIK3C2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PIK3C2B antibody detects endogenous levels of total PIK3C2B. Function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4, 5)P2. May be involved in EGF and PDGF signaling cascades.Subunit Structure: Part of a complex with ERBB2 and EGFR. Part of a complex with phosphorylated EGFR and GRB2. Interacts with phosphorylated EGFR and PDGFR, maybe indirectly. Interacts with GRB2 and SHC1.Similarity: Belongs to the PI3/PI4-kinase family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Microsome. Cell Membrane. Cytoplasm, Cytosol. Nucleus. Note=Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis. Tissue Specificity: Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level). Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney. Predicted Cross Reactivity: Pig, Horse, S |
Other Names | [C2 PI3K; phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; Phosphoinositide 3 Kinase C2 beta; Phosphoinositide 3-Kinase class 2, beta; phosphoinositide-3-kinase, class 2, beta polypeptide; PI3K C2beta; PtdIns 3 kinase C2 beta; PTDINS-3-kinase C2 beta; ptdIns-3-kinase C2 subunit beta] |
Gene, Accession # | [PIK3C2B], Gene ID: 5287, NCBI: NP_002637.3, UniProt: O00750 |
Catalog # | MBS9604138 |
Price | $240, $280 |
Order / More Info | PIK3C2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |