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Antigenic Specificity | Human Docking protein 5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.This protein is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP. |
Immunogen | Immunogen: Recombinant human Docking protein 5 protein |
Other Names | [Downstream of tyrosine kinase 5 Insulin receptor substrate 6 DOK5 C20orf180] |
Gene, Accession # | [DOK5], Gene ID: 55816, NCBI: NP_060901.2, UniProt: Q9P104 |
Catalog # | MBS7003768 |
Price | $160, $235 |
Order / More Info | Human Docking protein 5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |