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Antigenic Specificity | MMP-2 |
Clone | [3A8-C1-E8] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 4.72mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pa |
Immunogen | Immunogen: Purified recombinant human MMP-2 protein expressed in E Coli. Sensitivity: This antibody detects endogenous levels of MMP-2 and does not cross-react with related proteins. Sequence Similarities: Belongs to the peptidase M10A family.Contains 3 fibronectin type-II domains.Contains 4 hemopexin-like domains. |
Other Names | [72 kDa gelatinase; 72kD type IV collagenase; CLG 4; CLG 4A; CLG4; CLG4A; Collagenase Type 4 alpha; Collagenase type IV A; Gelatinase A; Gelatinase alpha; Gelatinase neutrophil; Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase; Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); Matrix Metalloproteinase 2; Matrix metalloproteinase II; Matrix metalloproteinase-2; MMP 2; MMP II; MMP-2; MMP2; MMP2_HUMAN; MONA; Neutrophil gelatinase; PEX; TBE 1; TBE-1], [CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II.] |
Gene, Accession # | [MMP-2], Gene ID: 4313, NCBI: NP_001121363.1, UniProt: P08253 |
Catalog # | MBS475445 |
Price | $335 |
Order / More Info | MMP-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |