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Antigenic Specificity | Human CD122/IL-3RB |
Clone | [TU27] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor beta chain also known as IL-2Rbeta, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rbeta chain can combine with either the common gamma subunit (gammac, CD132) alone or with the gammac subunit and the IL-2Ralpha subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. |
Immunogen | n/a |
Other Names | [Interleukin-2 receptor subunit beta; IL-2RB; p75; CD122; IL-2Rbeta] |
Gene, Accession # | [CD122/IL-3RB], Gene ID: 3560, NCBI: NP_000869.1, UniProt: P14784 |
Catalog # | MBS2559111 |
Price | $100, $125, $165 |
Order / More Info | Human CD122/IL-3RB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |