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Antigenic Specificity | AURORA-A KINASE |
Clone | [35C1] |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anri Human Aurora -A kinase monoclonal antibody, clone 35C1 recognizes human Aurora-A kinase also known as Aurora 2, breast tumor-amplified kinase and serine/threonine-protein kinase 6 or 15. Aurora kinase A is member of the Ser/Thr protein kinase family containing a single protein kinase domain, has a molecular weight of ~46kDa and is involved in mitotic spindle assembly (Ducat et al. 2004). Aurora-A kinase is reported to be overexpressed in many epithelial cancers and is thought to play an important role in tumourigenesis (Katayama et al. 2003). Aurora A kinase appears to facilitate phosphorylation of centrin and co-localizes with it at centrosomes with maximum expression through prophase to late metaphase (Lukasiewicz et al. 2011). |
Immunogen | n/a |
Other Names | [aurora kinase A; Aurora kinase A; aurora kinase A; ARK-1; Aurora-A kinase; IPL1-related kinase; aurora 2; aurora-related kinase 1; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; breast tumor-amplified kinase; breast-tumor-amplified kinase; hARK1; protein phosphatase 1, regulatory subunit 47; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine-protein kinase 15; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A; aurora kinase A; Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A], [AURKA; AURKA; AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; PPP1R47; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6; ARK-1; Aurora-related kinase 1; hARK1] |
Gene, Accession # | Gene ID: 6790, NCBI: NP_003591.2, UniProt: O14965 |
Catalog # | MBS212609 |
Price | $300 |
Order / More Info | AURORA-A KINASE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |