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Antigenic Specificity | PDGFRB |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PDGFRB Antibody detects endogenous levels of total PDGFRB. Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFRalpha) and PDGF receptor beta (PDGFRbeta). PDGFRalpha and PDGFRbeta share 75% to 85% sequence homology between their two intracellular kinase domains, while the kinase insert and carboxy-terminal tail regions display a lower level (27% to 28%) of homology (1). PDGFRalpha homodimers bind all PDGF isoforms except those containing PDGF D. PDGFRbeta homodimers bind PDGF BB and DD isoforms, as well as the PDGF AB h |
Immunogen | Immunogen: Recombinant protein of human PDGFRB |
Other Names | [CD140B; JTK12; PDGF-R-beta; PDGFR; PDGFR1] |
Gene, Accession # | [PDGFRB], Gene ID: 5159, NCBI: NP_002600.1, UniProt: P09619 |
Catalog # | MBS8516373 |
Price | $290 |
Order / More Info | PDGFRB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |