SEPT5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySEPT5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: SEPT5 antibody detects endogenous levels of total SEPT5. Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).Subunit Structure: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with SEPT2 and SEPT5. In platelets, associated with a complex containing STX4. Interacts with PRKN. This interaction leads to SEPT5 ubiquitination and degradation (By similarity).Post-translational Modifications: In platelets, phosphorylated in response to
ImmunogenImmunogen: A synthesized peptide derived from human SEPT5 Subcellular Location: Cytoplasm. Cytoplasm > Cytoskeleton. In platelets, found in areas surrounding alpha-granules. Tissue Specificity: Expressed at high levels in the CNS, as well as in heart and platelets (at protein level). Predicted Cross Reactivity: Pig, Bovine, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Dog (100%), Chicken (91%), Xenopus (91%)
Other Names[5 Sep; CDCrel 1; CDCREL; CDCrel-1; CDCREL1; Cell division control related protein 1; Cell division control-related protein 1; H5; HCDCREL 1; OTTHUMP00000197271; OTTHUMP00000197272; OTTHUMP00000197273; OTTHUMP00000197274; OTTHUMP00000197275; OTTHUMP00000197276; OTTHUMP00000197396; OTTHUMP00000197410; Peanut like 1; Peanut like 1 homolog; Peanut like protein 1; Peanut-like protein 1; Platelet glycoprotein Ib beta chain; PNUTL1; SEPT5; SEPT5_HUMAN; Septin 5; Septin-5]
Gene, Accession #[SEPT5], Gene ID: 5413, NCBI: NP_001009939.1, UniProt: Q99719
Catalog #MBS9610197
Price$240, $280
Order / More InfoSEPT5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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