Bik Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBik
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionBik Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family appear to control the activation of these enzymes. One such protein BIK was recently identified as an endoplasmic reticulum (ER)-residing pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family that stimulates mitochondrial release of cytochrome c following p53 induction of apoptosis. A significant fraction of BIK is found as an ER transmembrane protein, with most of the protein facing the cytosol. Restricting BIK to the ER membrane by replacing the transmembrane region with t
ImmunogenImmunogen: BIK antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human BIK. Buffer: Bik Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Bik; BP4; NBK; BIP1; Bcl-2-interacting killer; Apoptosis inducer NBK; BCL2-interacting killer (apoptosis-inducing)], [BIK; BIK; BP4; NBK; BIP1; NBK]
Gene, Accession #[BIK], Gene ID: 638, NCBI: CAG30276, UniProt: Q13323
Catalog #MBS151241
Price$375
Order / More InfoBik Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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