Spi-6, Mouse Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Spi-6, Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Spi-6, Mouse |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS),Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The polyclonal antibody recognizes mouse Spi-6, also known as serpin B9, a cytoplasmic serine protease inhibitor of ~42 kD. Spi-6 is expressed in dendritic cells, lymphocytes and specific cell types at immune-privileged sites. It inactivates granzyme B, a natural occurring inducer of programmed cell death. As such, Spi-6 functions as anti-apoptotic protein. In cytotxic T cells (CTL), Spi-6 is required to protect clonal bursts (expansion) from granzyme B induced cell death. However, it is not required for the development of memory cells. Expression of SPI-6 is of crucial importance in the escape of several tumors from a CTL response and is, therefore, a parameter that influences the feasibility of CTL-mediated immunother |
| Immunogen | Immunogen: Recombinant GST-Spi-6 |
| Other Names | n/a |
| Gene, Accession # | [Spi-6] |
| Catalog # | MBS584481 |
| Price | $555 |
| Order / More Info | Spi-6, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Zhang, M et al; Differential survival of cytotoxic T cells and memory cell precursors. J Immunol 2007, 178: 3483 2. Zhang, M et al; Serine protease inhibitor 6-deficient mice have increased neutrophil immunity to Pseudomonas aeruginosa. J Immunol 2007, 179: 4390 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies