Edit |   |
---|---|
Antigenic Specificity | Human CD55 |
Clone | [67] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD55 antibody, clone 67 recognizes the human CD55 cell surface antigen, a GPI linked molecule also known as decay accelerating factor (DAF). CD55 is expressed by a wide range of cell types. Erythrocyte expression is very weak. CD55 is the complement regulatory protein, decay accelerating factor (DAF) (Lublin and Atkinson 1989). Human CD55 is a ~70kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alterna |
Immunogen | Immunogen: K562 cells Histology Positive Control Tissue: Human Tonsil Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [complement decay-accelerating factor isoform 1 preproprotein; Complement decay-accelerating factor; complement decay-accelerating factor; CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CD_antigen: CD55], [CD55; CD55; CR; TC; DAF; CROM; CR; DAF] |
Gene, Accession # | [CD55], Gene ID: 1604, NCBI: NP_000565.1, UniProt: P08174 |
Catalog # | MBS212242 |
Price | $430 |
Order / More Info | Human CD55 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |