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Antigenic Specificity | Human C3 |
Clone | [AB01-3B4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human C3 antibody, clone AB01-384 recognizes complement C3. C3 is a central component of the classical, alternate and lectin pathways in the complement cascade which forms part of the innate immune defenses. The central position of C3 in the cascade has led to the emergence of immune invasion strategies by many human pathogens, including Staphylococcus aureus which expresses 2 proteins that interfere with the activation of C3 (Garcia et al. 2012). C3 Deficiencies in humans also show an increased susceptibility to bacterial infections in early childhood the development of autoimmune disease and kidney diseases (Ricklin et al. 2016). Conversely, complement over-activation can result in various disease pathologies, including inducti |
Immunogen | Immunogen: E Coli-derived recombinant human C3 (Gly1200-Asn1663), Swiss-Prot: P01024 |
Other Names | [CPAMD1], [C3; C3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; CPAMD1; ASP] |
Gene, Accession # | [C3], Gene ID: 718, NCBI: AAI50180.1, UniProt: P01024 |
Catalog # | MBS225710 |
Price | $300 |
Order / More Info | Human C3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |