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Antigenic Specificity | TIMP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Metalloproteinase inhibitor 4(TIMP4) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: The tissue inhibitors of metalloproteinases(TIMPs) inhibit matrix metalloproteinases(MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. expressed TIMP4 inhibits MMPs in vitro. TIMP4 gene is mapped to chromosome 3p25. TIMP-4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP4 (208-224aa YRGHLPLRKEFVDIVQP), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids. |
Other Names | [Metalloproteinase inhibitor 4; TIMP metallopeptidase inhibitor 4; Metalloproteinase inhibitor 4; TIMP 4; TIMP metallopeptidase inhibitor 4; TIMP-4; Timp4; TIMP4_HUMAN; Tissue inhibitor of metalloproteinase 4; Tissue inhibitor of metalloproteinases 4], [TIMP4; TIMP4; TIMP-4] |
Gene, Accession # | [TIMP4], Gene ID: 7079, NCBI: Q99727.1, UniProt: Q99727 |
Catalog # | MBS175349 |
Price | $315 |
Order / More Info | TIMP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |