Edit |   |
---|---|
Antigenic Specificity | NLRC4 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | guinea pig, human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody will recognize NLRC4 isoform 1 (116kD) and isoform 2 (40kD). This is a rabbit polyclonal antibody against NLRC4. It was validated on Western Blot and immunohistochemistryTarget Description: In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1, NOD1, and NOD2. These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NLRC4 |
Other Names | [NLR family CARD domain-containing protein 4 isoform a; NLR family CARD domain-containing protein 4; NLR family CARD domain-containing protein 4; NLR family CARD domain containing 4; CARD, LRR, and NACHT-containing protein; Clan protein; Caspase recruitment domain-containing protein 12; Ice protease-activating factor; Ipaf] |
Gene, Accession # | [NLRC4], Gene ID: 58484, NCBI: NP_067032, UniProt: Q9NPP4 |
Catalog # | MBS3224316 |
Price | $335 |
Order / More Info | NLRC4 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |