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Antigenic Specificity | ATG16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR through phosphorylation of autophagy protein APG1. ATG16, another member of the autophagy protein family, forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Beca |
Immunogen | Immunogen: ATG16 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 565 of human APG16 as the immunogen. |
Other Names | [Rabbit ATG16; ATG16; ATG16; ATG-16; ATG16; ATG-16; ATG 16; ATG 16; APG16; APTG 16] |
Gene, Accession # | [ATG16], Gene ID: 550097, UniProt: Q5I0B9 |
Catalog # | MBS5311540 |
Price | $430 |
Order / More Info | ATG16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |