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Antigenic Specificity | Nicotinic Acetylcholine Receptor alpha 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.77 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Nicotinic Acetylcholine Receptor alpha 4 protein. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have b |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment corresponding to a region within amino acids 53 and 280 of Nicotinic Acetylcholine Receptor alpha 4. |
Other Names | [BFNC; EBN; EBN1; FLJ95812; NACHR; NACHRA4; NACRA4; CHRNA4; neuronal nicotinic acetylcholine receptor alpha-4 subunit; cholinergic receptor; nicotinic; alpha polypeptide 4 an] |
Gene, Accession # | Gene ID: 1137, NCBI: NP_000735.1, UniProt: P43681 |
Catalog # | MBS9405151 |
Price | $320 |
Order / More Info | Nicotinic Acetylcholine Receptor alpha 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |