PAPP A Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PAPP A |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Pappalysin-1(PAPPA) detection. Tested with WB, IHC-P in Human. Background: Pappalysin-1, also known as DIPLA1, is a protein that in humans is encoded by the PAPPA gene. It is mapped to 9q33.1. PAPPA is found in the ovarian follicles, follicular fluid, luteal cells, and fallopian tubes of nonpregnant women and in the seminal vesicles and seminal fluid of males. This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. It |
| Immunogen | Immunogen: E Coli-derived human PAPP A recombinant protein (Position: R95-Q388). Human PAPP A shares 88% amino acid (aa) sequence identity with mouse PAPP A. Ig Type: Rabbit IgG |
| Other Names | [Pappalysin-1; ASBABP2; Aspecific BCL2 ARE binding protein 2; Differentially placenta 1 expressed protein; DIPLA1; IGF dependent IGFBP 4 protease; IGF-dependent IGFBP-4 protease; IGFBP 4ase; IGFBP-4ase; IGFBP4ase; Insulin like growth factor dependent IGF binding protein 4 protease; Insulin-like growth factor-dependent IGF-binding protein 4 protease; PAPA; PAPP A; PAPP-A; PAPP1_HUMAN; PAPPA; PAPPA1; Pappalysin 1 precursor; Pappalysin-1; Pregnancy Associated Plasma Protein A; Pregnancy associated plasma protein A pappalysin 1; Pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1], [PAPPA; PAPPA; PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase; IGF-dependent IGFBP-4 protease; IGFBP-4ase; PAPP-A] |
| Gene, Accession # | [PAPP A], Gene ID: 5069, NCBI: NP_002572.2, UniProt: Q13219 |
| Catalog # | MBS178360 |
| Price | $315 |
| Order / More Info | PAPP A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Oxvig, C., Sand, O., Kristensen, T., Gleich, G. J., Sottrup-Jensen, L. Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein. J. Biol. Chem. 268: 12243-12246, 1993. 2. Overgaard, M. T., Haaning, J., Boldt, H. B., Olsen, I. M., Laursen, L. S., Christiansen, M., Gleich, G. J., Sottrup-Jensen, L., Conover, C. A., Oxvig, C. Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor. J. Biol. Chem. 275: 31128-31133, 2000. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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