Edit |   |
---|---|
Antigenic Specificity | HJV - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against HFE2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HFE2 |
Other Names | [hemojuvelin isoform c; Hemojuvelin; hemojuvelin; hemojuvelin BMP co-receptor; Hemochromatosis type 2 protein; RGM domain family member C] |
Gene, Accession # | [HJV], Gene ID: 148738, NCBI: NP_973733, UniProt: Q6ZVN8 |
Catalog # | MBS3211334 |
Price | $335 |
Order / More Info | HJV - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |