Human Heme Oxygenase 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Heme Oxygenase 1
Clone[PAT1D6AT]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a k
FormatProtein A purified
Size0.005 mg, 0.02 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Flow cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionHMOX1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is then converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HMOX1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme Oxygenase-1 is involved in the regulation of cardiovascular function and its adaptive response to a variety of stressors. HMOX1 is induced in the colon of ulcerative colitis. HMOX1 is found to overexpress with a higher extent of intraplaque angiogenesis implies a multi-faceted role for HMOX1 in modulating the progression of atherosclerosis. HMOX1 expression reduced LPS-stimulated secretion of MCP-1, IL-6, IL-10, and TNF-alpha in murine and human macrophages.
ImmunogenImmunogen: Anti-human HMOX1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HMOX1 amino acids 1-266 purified from E Coli
Other Names[HO-1; HSP32; bK286B10; HMOX-1; Heme oxygenase 1; HMOX1; HO; HO1; HMOX1; Heme Oxygenase 1, Mouse Human], [HMOX1; HMOX1; HO-1; HSP32; HMOX1D; bK286B10; HO; HO1; HO-1]
Gene, Accession #[HMOX1], Gene ID: 3162, NCBI: NP_002124.1, UniProt: P09601
Catalog #MBS146978
Price$140, $205, $505
Order / More InfoHuman Heme Oxygenase 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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