SAD1 (BRSK1) (N-term), 108-139 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySAD1 (BRSK1) (N-term), 108-139
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis SAD1 (BRSK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human SAD1 (BRSK1). BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell
Immunogenn/a
Other Names[Serine/threonine-protein kinase BRSK1; Brain-selective kinase 1; Brain-specific serine/threonine-protein kinase 1; BR serine/threonine-protein kinase 1; Serine/threonine-protein kinase SAD-B; Synapses of Amphids Defective homolog 1; SAD1 homolog; hSAD1; BRSK1; KIAA1811; SAD1; SADB]
Gene, Accession #[BRSK1], Gene ID: 84446, NCBI: NP_115806.1, UniProt: Q8TDC3
Catalog #MBS9210933
Price$165, $370
Order / More InfoSAD1 (BRSK1) (N-term), 108-139 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLu, R., et al., J. Biol. Chem. 279(30):31164-31170 (2004). Lizcano, J.M., et al., EMBO J. 23(4):833-843 (2004).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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