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Antigenic Specificity | CKIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha', and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against an 18 amino acid peptide from near the carboxy terminus of human CKIP1. |
Other Names | [Casein kinase-2-interacting protein 1, pleckstrin homology domain containing, family O member 1, PLECKHO1] |
Gene, Accession # | [CKIP1], Gene ID: 51177, NCBI: NP_057358 |
Catalog # | MBS9412634 |
Price | $320 |
Order / More Info | CKIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |