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Antigenic Specificity | DTNBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton re |
Immunogen | Immunogen: Recombinant funsion protein containing a sequence corresponding to amino acids 1-351 of human DTNBP1 (NP 115498.2). |
Other Names | [SDY; DBND; HPS7; My031; BLOC1S8] |
Gene, Accession # | [DTNBP1], Gene ID: 84062, NCBI: Q96EV8.1, UniProt: Q96EV8 |
Catalog # | MBS8550403 |
Price | $280 |
Order / More Info | DTNBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |