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Antigenic Specificity | RHG17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total RHG17 protein. Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the c |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of humanRHG17. |
Other Names | [NADRIN; neuron-associated developmentally regulated protein; RHG17; rho GTPase activating protein 17; RhoGAP interacting with CIP4 homologs 1] |
Gene, Accession # | [RHG17], Gene ID: 55114, NCBI: NP_001006635.1, UniProt: Q68EM7 |
Catalog # | MBS9412378 |
Price | $200, $255 |
Order / More Info | RHG17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |