Edit |   |
---|---|
Antigenic Specificity | FGF21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. FGF21(Fibroblast growth factor 21) is a protein that in humans is encoded by the FGF21 gene, which is also a member of the fibroblast growth factor(FGF) family. The FGF21 gene is mapped on 19q13.33. Using RT-PCR, Fgf21 was expressed in several types of adipose tissue in mice, including subcutaneous and epididymal fat pads and brown adipose tissue. The level of Fgf21 expression in adipose tissue was comparable to that in liver. FGF21 stimulates glucose uptake in adipocytes but not in other cell types. This effect is additive to the activity of insulin. FGF21 treatment of adipocytes is associated with phosphorylation of FRS2, a protein linking FGF receptors to the Ras/MAP kinase pathway. F |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FGF21 (43-58aa QVRQRYLYTDDAQQTE), different from the related rat and mouse sequences by two amino acids. |
Other Names | [Fibroblast growth factor 21(FGF-21); fibroblast growth factor 21; FGF 21; FGF-21; Fgf21; FGF21_HUMAN; FGFL; Fibroblast growth factor 21; PRO10196; UNQ3115], [FGF21; FGF21; FGF-21] |
Gene, Accession # | [FGF21], Gene ID: 26291, NCBI: Q9NSA1.1, UniProt: Q9NSA1 |
Catalog # | MBS175449 |
Price | $280 |
Order / More Info | FGF21 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |