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Antigenic Specificity | HLA-DRB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificiti |
Immunogen | Immunogen: Recombinant protein of human HLA-DRB1 (NP 002115.2). |
Other Names | [major histocompatibility complex, class II, DR beta 1; HLA class II histocompatibility antigen, DRB1-15 beta chain; DW2.2/DR2.2; MHC class II antigen DRB1*15] |
Gene, Accession # | [HLA-DRB1], Gene ID: 3123, NCBI: NP_002115.2, UniProt: P01911 |
Catalog # | MBS8573519 |
Price | $280 |
Order / More Info | HLA-DRB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |