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Antigenic Specificity | IRF-4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IRF-4 Polyclonal Antibody detects endogenous levels of IRF-4 protein. Interferon regulatory factor 4 encoded by IRF4 belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced tra |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human IRF-4 at AA range: 250-330 |
Other Names | [Rabbit IRF-4; IRF4; MUM1; Interferon regulatory factor 4; IRF-4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5] |
Gene, Accession # | [IRF-4], Gene ID: 3662, NCBI: NP_001182215.1, UniProt: Q15306 |
Catalog # | MBS9702343 |
Price | $130, $220, $325 |
Order / More Info | IRF-4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |