FOLR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFOLR1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total FOLR1 protein. Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.Elwood P.C., J. Biol. Chem. 264:14893-14901(1989).Lacey S.W., J. Clin. Invest. 84:715-720(1989).Campbell I.G., Cancer Res. 51:5329-5338(1991).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human FOLR1.
Other Names[Folate receptor alpha; FR-alpha; Folate receptor 1; Folate receptor; adult]
Gene, Accession #[FOLR1], Gene ID: 2348, NCBI: NP_000793.1, UniProt: P15328
Catalog #MBS9412548
Price$200, $255
Order / More InfoFOLR1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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