AKT2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-AKT2 antibody, protein, ELISA kits.
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| Antigenic Specificity | AKT2 |
| Clone | [10C6] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for AKT2 detection. Tested with WB, ICC in Human.Background: AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. This gene is mapped to 19q13.2. AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrat |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human AKT2 (454-481aa DRYDSLGLLELDQRTHFPQFSYSASIRE), different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid. |
| Other Names | [RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta; AKT2; V-akt murine thymoma viral oncogene homolog 2] |
| Gene, Accession # | [AKT2], Gene ID: 208, NCBI: NP_001317440.1, UniProt: P31751 |
| Catalog # | MBS1752014 |
| Price | $315 |
| Order / More Info | AKT2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., Testa, J. R. Amplification of AKT2 in human pancreatic cancer cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Nat. Acad. Sci. 93: 3636-3641, 1996. 2. Li, X., Monks, B., Ge, Q., Birnbaum, M. J. Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1-alpha transcription coactivator. Nature 447: 1012-1016, 2007. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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