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Antigenic Specificity | Human Amyloid Beta A4 Protein |
Clone | [PJ4H9AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: APP is a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in the APP gene are implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). |
Immunogen | Immunogen: Anti-human APP mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human APP amino acids 18-289 purified from E Coli. |
Other Names | [APP; Amyloid Beta A4 Protein, Mouse Human; Amyloid beta A4 protein; Alzheimer disease amyloid protein; ABPP; APPI; APP; PreA4; Cerebral vascular amyloid peptide; CVAP; Protease nexin-II; PN-II; A4; AD1; AAA; PN2; ABETA; CTFgamma], [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)] |
Gene, Accession # | [APP], Gene ID: 351, NCBI: NP_000475.1 |
Catalog # | MBS140213 |
Price | $140, $205, $505 |
Order / More Info | Human Amyloid Beta A4 Protein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |