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Antigenic Specificity | Human Podoplanin |
Clone | [18H5 / IgG1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.025 mg |
Concentration | 200 ug/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The unconjugated monoclonal antibody will detect native human Podoplanin in WB and on the surface of human LEC. Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid (aa) precursor (NP_006465). It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207228) and a short cytoplasmic tail (aa 229-238). The ECD contains abundant Ser/Thr residues that could serve as potential Olinked glycosolation sites. The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two |
Immunogen | Immunogen: MDCK cells stably expressing gp36 (Podoplanin) protein. Conjugation: PE. Preparation: Monoclonal antibodies were produced with the help of BALB/c mice using MDCK cells stably expressing gp36 (Podoplanin) protein as the immunizing antigen. |
Other Names | [human Podoplanin-PE (#18H5); Glycoprotein 36; GP36; T1-alpha; PA2.26 antigen], [PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; GP36; Gp36; T1A] |
Gene, Accession # | Gene ID: 10630, NCBI: NP_001006625.1, UniProt: Q86YL7 |
Catalog # | MBS690117 |
Price | $250 |
Order / More Info | Human Podoplanin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Breiteneder-Geleff et al, Am J Pathol 154:385, 1999 2. Kerjaschki et al, Nature Med 12:230, 2006 3. Kriehuber et al, J Exp Med 194:797, 2001 4. Zimmer. et al, Biochem J 341:277, 1999 5. Kato et al, Tumour Biol 26:195, 2005 6. Katsue-Inoue et al, J Biol Chem 282:25993, 2007 7. Kato et al, Oncogene 23:8552, 2004 8. Schacht. et al, Am J Pathol 166:913, 2005 9. Mishima et al, Acta Neuropathol 111:483, 2006 |