GRB2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRB2
Clone[3B2-G2-E5]
Host SpeciesMouse
Reactive Specieshuman, rat, mouse, monkey
IsotypeIgG1
Formatunconjugated
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody detects endogenous levels of GRB2 and does not cross-react with related proteins. Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Purified recombinant human GRB2 protein fragments expressed in E Coli.
Other Names[Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb2; GRB2_HUMAN; Grb3 3]
Gene, Accession #[GRB2], Gene ID: 2885, NCBI: NP_002077.1, UniProt: P62993
Catalog #MBS9400488
Price$200, $255
Order / More InfoGRB2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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