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Antigenic Specificity | GPAT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GPAT1 Antibody: Glycerol-3-phosphate acyltransferase 1 (GPAT1), one of four known GPAT isoforms, is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis; steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipog |
Immunogen | Immunogen: GPAT1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human GPAT1. Buffer: GPAT1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [GPAT1; GPAT; GPAT1; KIAA1560; Glycerol-3-phosphate acyltransferase 1; mitochondrial; GPAT-1; glycerol-3-phosphate acyltransferase, mitochondrial], [GPAM; GPAM; GPAT; GPAT1; GPAT1; KIAA1560; GPAT-1] |
Gene, Accession # | [GPAM], Gene ID: 57678, NCBI: NP_065969, UniProt: Q9HCL2 |
Catalog # | MBS150163 |
Price | $375 |
Order / More Info | GPAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |