TYROBP (C-term), 85-113 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TYROBP (C-term), 85-113 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TYROBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TYROBP. TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with |
| Immunogen | n/a |
| Other Names | [TYRO protein tyrosine kinase-binding protein; DNAX-activation protein 12; Killer-activating receptor-associated protein; KAR-associated protein; TYROBP; DAP12; KARAP] |
| Gene, Accession # | [TYROBP], Gene ID: 7305, NCBI: NP_001166985.1, UniProt: O43914 |
| Catalog # | MBS9214783 |
| Price | $165, $370 |
| Order / More Info | TYROBP (C-term), 85-113 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Chen, X., et al. Blood 113(14):3226-3234(2009) Sulonen, A.M., et al. J. Neuroimmunol. 206 (1-2), 86-90 (2009) Lanier, L.L. Immunol. Rev. 227(1):150-160(2009) Schleinitz, N., et al. PLoS ONE 4 (7), E6264 (2009) |
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MYBIOSOURCE INC.
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