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Antigenic Specificity | ACVR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least four isoforms of ACVR1 are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1B or ACVR1C. ACVR1 Antibody: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. Unlike ACVR1B and ACVR1C, ACVR1, also known as activin receptor-like kinase 2 (ALK2), can not transduce activin-mediated signaling, but will transduce BMP and Mullerian inhibiting substance (MIS) group signaling. It is thought that ACVR1 also inhibits activin signaling by blocking th |
Immunogen | Immunogen: ACVR1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human ACVR1. Buffer: ACVR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ACVR1; FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2; Activin receptor type-1; Activin receptor type I; ACTR-I; activin A receptor, type I], [ACVR1; ACVR1; FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2; ACVRLK2; ACTR-I; ALK-2; SKR1; TSR-I] |
Gene, Accession # | [ACVR1], Gene ID: 90, NCBI: NP_001096, UniProt: Q04771 |
Catalog # | MBS150372 |
Price | $375 |
Order / More Info | ACVR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |