CNKSR3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CNKSR3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CNKSR3 Antibody detects endogenous levels of CNKSR3. Description: Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).Subunit Structure: Interacts with epithelial sodium channel ENaC. Interacts directly with SCNN1A (ENaC subunit alpha) and SCNN1B (ENaC subunit beta) C-terminal tails. Interacts with ENaC regulatory proteins NEDD4L, RAF1 and SGK1.Similarity: The PDZ domain is required for interaction with ENaC and SGK1, but not for interaction with NEDDL4 and RAF1. Belongs to the CNKSR fami |
| Immunogen | Immunogen: A synthesized peptide derived from human CNKSR3. Tissue Specificity: Up-regulated by aldosterone (at protein level). |
| Other Names | [CNK homolog protein 3; CNK3; CNKSR family member 3; Connector enhancer of kinase suppressor of ras 3; Connector enhancer of KSR 3; MAGI1; Maguin like protein; Membrane associated guanylate kinase interacting protein like 1; Membrane associated guanylate kinase, WW and PDZ domain containing 1; RP11 486M3 1; RP11 486M3.1] |
| Gene, Accession # | [CNKSR3], Gene ID: 154043, NCBI: NP_775786.2, UniProt: Q6P9H4 |
| Catalog # | MBS9611652 |
| Price | $240, $280 |
| Order / More Info | CNKSR3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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