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Antigenic Specificity | Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) |
Clone | [ELN/1981] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hype |
Immunogen | Immunogen: Recombinant full-length human Elastin protein Cellular Localization: Secreted and Extracellular Space |
Other Names | [Elastin; ELN; SVAS; Tropoelastin; WBS; WS] |
Gene, Accession # | [ELN], Gene ID: 2006, NCBI: NP_000492.2, UniProt: P15502 |
Catalog # | MBS4380433 |
Price | $190, $340, $340 |
Order / More Info | Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody from MYBIOSOURCE INC. |
Product Specific References | Fazio, M.J., Mattei, M.G., Passage, E., Chu, M.L., Black, D., Solomon, E., Davidson, J.M. and Uitto, J. 1991. Human elastin gene: new evidence for localization to the long arm of chromosome 7. Am. J. Hum. Genet. 48: 696-703. |