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Antigenic Specificity | SKP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti SKP2 antibody recognizes S-phase kinase-associated protein 2 (SKP2), also known as F-box protein Skp2, p45skp2 and Cyclin-A/CDK2-associated protein p45. SKP2 is a ubiquitin ligase, a critical component of the SKP2-SCF complex (Nakayama and Nakayama 2005). It is frequently overexpressed in human cancer (Chiarle et al. 2002). Loss of SKP2 can promote senescence in response to oncogene activation (Lin et al. 2010). It plays a role in regulating cancer stem cell populations (Chan et al. 2013). |
Immunogen | Immunogen: A synthetic peptide corresponding to amino acids 171-182 of human SKP2 |
Other Names | [SKP2], [SKP2; SKP2; p45; FBL1; FLB1; FBXL1; FBXL1] |
Gene, Accession # | [SKP2], Gene ID: 6502, NCBI: NP_001230049.1, UniProt: Q13309 |
Catalog # | MBS225593 |
Price | $375 |
Order / More Info | SKP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |