NKRF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNKRF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: NKRF antibody detects endogenous levels of total NKRF. Function: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.Subunit Structure: Interacts with NF-kappa-B. Interacts with XRN2 (PubMed:24462208).
ImmunogenImmunogen: A synthesized peptide derived from human NKRF Subcellular Location: Nuclear Tissue Specificity: Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (92%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Other Names[ITBA4; NF kappa B repressing factor; NFKB repressing factor; NRF; Transcription factor NRF]
Gene, Accession #[NKRF], Gene ID: 55922, NCBI: NP_001166958.1, UniProt: O15226
Catalog #MBS9609072
Price$240, $280
Order / More InfoNKRF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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