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Antigenic Specificity | NKRF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NKRF antibody detects endogenous levels of total NKRF. Function: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.Subunit Structure: Interacts with NF-kappa-B. Interacts with XRN2 (PubMed:24462208). |
Immunogen | Immunogen: A synthesized peptide derived from human NKRF Subcellular Location: Nuclear Tissue Specificity: Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (92%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [ITBA4; NF kappa B repressing factor; NFKB repressing factor; NRF; Transcription factor NRF] |
Gene, Accession # | [NKRF], Gene ID: 55922, NCBI: NP_001166958.1, UniProt: O15226 |
Catalog # | MBS9609072 |
Price | $240, $280 |
Order / More Info | NKRF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |