Edit |   |
Antigenic Specificity | Hsp90 |
Clone | [AC-16] |
Host Species | Mouse |
Reactive Species | human, rabbit, rat, mouse, chicken, Achyla, Wheat Germ, Sf9 cell line |
Isotype | IgG2b |
Format | ATTO 680 conjugate |
Size | 0.2 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: This antibody is reactive with both the constitutive and the inducible form of Hsp90. It does not bind to the native form and does not recognize Hsp90 from E.coli or yeast. Scientific Background: Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (1-4). Despite its label of being a heat-shock protein, hsp90 is one of the most highly expressed proteins in unstressed cells (1-2% of cytosolic protein). It carries out a number of housekeeping functions - including controlling the activity, turnover, and traf |
Immunogen | n/a |
Other Names | [Hsp84; Hsp86; Hsp90; Hsp89; Hsp90Beta; Hsp90A; Hsp90AA1; Hsp90AB1; Hsp90B; Hsp90N; HspC1; HspC2; HspCA; HspCAL1; HspCAL4; HspCB; HspN; LAP2], [NF1P5; NF1L5] |
Gene, Accession # | Gene ID: 4768, NCBI: AAM90675.1, UniProt: Q8LLI5 |
Catalog # | MBS800061 |
Price | $495 |
Order / More Info | Hsp90 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 2. Pearl H, et al. (2001) Adv Protein Chem 59:157-186. 3. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 4. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 5. Pratt W, Toft D. (1997) Endocr Rev 18: 306-360. 6. Pratt WB. (1998) Proc Soc Exptl Biol Med 217: 420-434. 7. Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91: 8324- 8328. |