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Antigenic Specificity | DLX5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. |
Immunogen | Immunogen: Recombinant human Homeobox protein DLX-5 protein |
Other Names | [Homeobox protein DLX-5; DLX5] |
Gene, Accession # | [DLX5], Gene ID: 1749, NCBI: NP_005212.1, UniProt: P56178 |
Catalog # | MBS7044298 |
Price | $160, $235 |
Order / More Info | DLX5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |