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Antigenic Specificity | CANX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. Calnexin was first identified as being involved in the assembly of murine class I histocompatibility molecules (1,2). Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide int |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Calnexin: Calnexin; CNX; FLJ26570; IP90; P90], [CANX; CANX; CNX; P90; IP90] |
Gene, Accession # | [CANX], Gene ID: 821, NCBI: P27824.2, UniProt: P27824 |
Catalog # | MBS125776 |
Price | $200, $275, $430 |
Order / More Info | CANX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |