CD11a / Integrin alphaL / LFA-1 alpha Chain Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CD11a / Integrin alphaL / LFA-1 alpha Chain antibody, protein, ELISA kits.
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| Antigenic Specificity | CD11a / Integrin alphaL / LFA-1 alpha Chain |
| Clone | [DF1524] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation. |
| Immunogen | Immunogen: Human CD11a protein |
| Other Names | [Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide; Integrin alpha-L; ITGAL; Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain; LFA 1 alpha (LFA1A); Ly15; Ly21; p180], [ITGAL; ITGAL; CD11A; LFA-1; LFA1A; CD11A; LFA-1A] |
| Gene, Accession # | [ITGAL], Gene ID: 3683, NCBI: NP_001107852.1, UniProt: P20701 |
| Catalog # | MBS439260 |
| Price | $190, $340, $340 |
| Order / More Info | CD11a / Integrin alphaL / LFA-1 alpha Chain Antibody from MYBIOSOURCE INC. |
| Product Specific References | Knapp et al. (Eds.), Leukocyte Typing IV, 1989: Sections N1 (pp. 543.551), N1.l (pp. 551553); N1.2 (pp. 553554); N1.3 (pp. 555558); N1.8 (pp. 566570); N1.9 (pp. 570574); N14.4 (pp. 689693). Petruzzelli L et al. Activation of lymphocyte function-associated molecule-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) mimicked by an antibody directed against CD18. J Immunol 1995, 155(2):854-866. Edwards CP et al. Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1. J Biol Chem 1998, 273(44):28937-44. Shang XZ and Issekutz AC. Contribution of CD11a/CD18, CD11b/CD18, ICAM-1 (CD54) and -2 (CD102) to human monocyte migration through endothelium and connective tissue fibroblast barriers. Eur J Immunol 1998, 28(6):1970-1979. Tian L et al. The neuronal glycoprotein telencephalin is a cellular ligand for the CD11a/CD18 leukocyte integrin. J Immunol 1997, 158(2):928-936 |
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MYBIOSOURCE INC.
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