Trophinin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTrophinin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Trophinin antibody is human, mouse and rat reactive. Multiple isoforms of Trophinin are known to exist. Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential
ImmunogenImmunogen: Trophinin antibody was raised against a 16 amino acid peptide near the amino terminus of human Trophinin. Buffer: Supplied in PBS containing 0.02% sodium azide. Positive Control 1: Rat Liver Tissue Lysate
Other Names[Trophinin; TRO; MAGE-d3; MAGED3], [TRO; TRO; MAGED3; MAGE-d3; KIAA1114; MAGED3]
Gene, Accession #[TRO], Gene ID: 7216, NCBI: NP_001034794, UniProt: Q12816
Catalog #MBS154375
Price$375
Order / More InfoTrophinin Antibody from MYBIOSOURCE INC.
Product Specific ReferencesFukuda MN, Sato T, Nakayama J, et al. Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation. Genes Dev. 1995; 9:1199-210. Ma L, Yin M, Wu X, et al. Expression of trophinin and bystin identifies distinct cell types in the germinal zones of adult rat brain. Eur. J. Neurosci. 2006; 23:2265-76. Tamura N, Sugihara K, Akama TO, et al. Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-d. Cell Cycle 2011; 10:135-43. Chen KY, Lee YC, Lai JM, et al. Identification of trophinin as an enhancer for cell invasion and a prognostic factor for early stage lung cancer. Eur. J. Cancer. 2007; 43:782-90.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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