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Antigenic Specificity | Trophinin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Trophinin antibody is human, mouse and rat reactive. Multiple isoforms of Trophinin are known to exist. Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential |
Immunogen | Immunogen: Trophinin antibody was raised against a 16 amino acid peptide near the amino terminus of human Trophinin. Buffer: Supplied in PBS containing 0.02% sodium azide. Positive Control 1: Rat Liver Tissue Lysate |
Other Names | [Trophinin; TRO; MAGE-d3; MAGED3], [TRO; TRO; MAGED3; MAGE-d3; KIAA1114; MAGED3] |
Gene, Accession # | [TRO], Gene ID: 7216, NCBI: NP_001034794, UniProt: Q12816 |
Catalog # | MBS154375 |
Price | $375 |
Order / More Info | Trophinin Antibody from MYBIOSOURCE INC. |
Product Specific References | Fukuda MN, Sato T, Nakayama J, et al. Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation. Genes Dev. 1995; 9:1199-210. Ma L, Yin M, Wu X, et al. Expression of trophinin and bystin identifies distinct cell types in the germinal zones of adult rat brain. Eur. J. Neurosci. 2006; 23:2265-76. Tamura N, Sugihara K, Akama TO, et al. Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-d. Cell Cycle 2011; 10:135-43. Chen KY, Lee YC, Lai JM, et al. Identification of trophinin as an enhancer for cell invasion and a prognostic factor for early stage lung cancer. Eur. J. Cancer. 2007; 43:782-90. |