NRAS (C-term), 147-179 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNRAS (C-term), 147-179
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: porcine)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB)
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DescriptionThis NRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the C-terminal region of human NRAS. NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
Immunogenn/a
Other Names[GTPase NRas; Transforming protein N-Ras; NRAS; HRAS1]
Gene, Accession #[NRAS], Gene ID: 4893, NCBI: NP_002515.1, UniProt: P01111
Catalog #MBS9213867
Price$165, $370
Order / More InfoNRAS (C-term), 147-179 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSmalley,K.S., Cancer Res. 68 (14), 5743-5752 (2008) Banerji,U., Mol. Cancer Ther. 7 (4), 737-739 (2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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