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Antigenic Specificity | FNIP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1. FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the carboxy terminus of human FNIP2. |
Other Names | [Folliculin interacting protein 2, FNIPL] |
Gene, Accession # | [FNIP2], Gene ID: 57600, NCBI: NP_065891 |
Catalog # | MBS9404910 |
Price | $320 |
Order / More Info | FNIP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |