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Antigenic Specificity | RNF6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator. |
Immunogen | Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF6 protein (1-298AA) Conjugation: Non-conjugated |
Other Names | [E3 ubiquitin-protein ligase RNF6; RNF6; SPG2] |
Gene, Accession # | [RNF6], Gene ID: 6049, NCBI: NP_005968.1, UniProt: Q9Y252 |
Catalog # | MBS7053397 |
Price | $160, $235 |
Order / More Info | RNF6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |