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Antigenic Specificity | IL7R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total IL7R protein. The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human IL7R. |
Other Names | [IL7R; CD127; CDW127; IL-7R-alpha; IL7RA] |
Gene, Accession # | [IL7R], Gene ID: 3575, NCBI: NP_002176.2, UniProt: P16871 |
Catalog # | MBS9404145 |
Price | $255 |
Order / More Info | IL7R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |