Mouse IL6R Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse IL6R |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (sIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a sIL-6R protein are able to mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signalling. Through this so-called 'trans-signalling' mechanism, IL-6 is able to stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and sIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer. |
| Immunogen | Immunogen: Recombinant Mouse IL-6R/CD126 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
| Other Names | [interleukin-6 receptor subunit alpha isoform 3; Interleukin-6 receptor subunit alpha; interleukin-6 receptor subunit alpha; interleukin 6 receptor; IL-6R 1; Membrane glycoprotein 80; gp80; CD_antigen: CD126] |
| Gene, Accession # | [IL6R ], Gene ID: 3570 |
| Catalog # | MBS2544536 |
| Price | $215, $330, $500 |
| Order / More Info | Mouse IL6R Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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