SET, Phosphatase 2A Inhibitor I2PP2A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySET, Phosphatase 2A Inhibitor I2PP2A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatammonium sulfate precipitate
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionHuman SET was originally identified as part of the SET-CAN fusion gene produced by a somatic translocation event in a patient with acute undifferentiated leukemia. In developing kidney, SET is highly expressed in the zone of nephron morphogenesis. SET has been shown to be a potent and specific inhibitor of protein phosphatase 2A, a family of major serine/threonine phosphatases involved in regulating cell proliferation and differentiation. SET is also involved in the regulation of renal cell proliferation and tumorigenesis. SET mRNA expression is markedly reduced in cells rendered quiescent by serum starvation, contact inhibition, or differentiation. SET protein expression is also much greater in developing rat and human kidney than in fully
ImmunogenImmunogen: Synthetic peptide derived from the human SET protein
Other Names[SET; SET translocation (myeloid leukemia-associated); Protein SET; Phosphatase 2A inhibitor; I2PP2A; I-2PP2A; Template-activating factor I; TAF-I; HLA-DR-associated protein II; PHAPII; Inhibitor of granzyme A-activated DNase; IGAAD2PP2A; IGAAD; I2PP2A; PHAPII; TAF-IBETA], [COL4A3BP; COL4A3BP; CERT; GPBP; CERTL; STARD11; CERT; STARD11; hCERT; GPBP; StARD11]
Gene, Accession #Gene ID: 10087, NCBI: NP_001123577.1, UniProt: Q9Y5P4
Catalog #MBS396109
Price$340
Order / More InfoSET, Phosphatase 2A Inhibitor I2PP2A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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